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Report on Results of Chromosome Aberration Test
using Cultured Mammalian Cells

Attached paper 2	7. Judgment of Results and Reference Matters
	(1)	Judgment of results
	(2)	Reference matters

In Japanese

7. Judgment of Results and Reference Matters

(1) Judgment of results

Judgment (Circle either one.)			Positive Negative
Reasons for Judgment
D₂₀ value	Structural aberration	Short-term treatment process		-S9 mix	- h treatment	mg/ml
				+S9 mix	- h treatment	mg/ml
		Continuous treatment process			- h treatment	mg/ml
					- h treatment	mg/ml
	Numerical aberration	Short-term treatment process		-S9 mix	- h treatment	mg/ml
				+S9 mix	- h treatment	mg/ml
		Continuous treatment process			- h treatment	mg/ml
					- h treatment	mg/ml

[Remarks]

The D₂₀ value is an estimated dosage of the test substance required for inducing aberration in 20% metaphasic cells, and enter in accord with types of aberration for the test series judged positive.

(2) Reference matters

[Remarks] Enter opinions, etc. of the study director on the test results in the column of "Reference matters".

INDEX

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