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Ordinance on Prevention of Hazards Due to
Specified Chemical Substances


Ministry of Labour Ordinance No. 39 of September 30, 1972


Supplementary Provisions

(Date of Enforcement)

Article 1.  This Ministry of Labour Ordinance will be put into effect on October 1, 1972, provided that this does not apply in respect to Article 4, which will be put into effect on October 1, 1973.

(Abrogation)

Article 2.  The Ordinance on Prevention of Hazards Due to Specified Chemical Substances, etc. (Ministry of Labour Ordinance No. 11 of 1971) will be abolished.

(Interim Measures concerning Local Exhaust Ventilation Systems)

Article 3.   In terms of indoor workshops where dispersion occurs of the dust of coal tar, the provisions as set forth in Article 5 will not be applied to the workshops until September 30, 1973.

(Interim Measures concurring Dust Exclusion Devices)

Article 4.   In term of exhaust gas disposition cylinders from which to emit the gases containing dusts of coal tar, the provision of Article 9 will not be applied until September 30. 1973.

(Interim Measures concurring Operations Chiefs of Work on Specified Chemical Substances, etc.)

Article 5.   In spite of the provisions of Article 27, the employer may appoint an operations chief of work on specified chemical substances, etc., from among persons holding the health supervisor's license until September 30, 1974.

Supplementary Provisions

(Ministry of Labour Ordinance No. 26 of September 30, 1975)

(Date of Enforcement)

Article 1.  This Ministry of Labour Ordinance will be put into effect on October 1, 1975, provided that the following provisions will be put into effect on the dates shown in the respective items.

(1)   Amended provision of contents (exclusive of the portion thereby to revise "Article 50" into "Article 50-2"), amended provision thereby to add one article following Article 12, amended provision thereby to revise Article 20 (exclusive of the portions thereby to revise "item (8)" into "item (9)," "item (7)" into "item (8)," and to add one item following item (6), amended provisions thereby to revise Article 22, Article 24 and Article 25, amended provision thereby to add three articles following Article 38, amended provision thereby to add one chapter next to Chapter V (exclusive of the portions related to Article 38-9 and Article 38-12), amended provision thereby to add one article following Article 52, and amended provision thereby to add the form following Form No. 10: January 1, 1976. 

(2)   Amended provisions thereby to revise Article 3, the heading before Article 4 and Article 4, amended provisions thereby to revise Article 6, (restricted to that of "The provisions of the preceding Article, indoor workshops" into "The provisions of the preceding two Articles, indoor workshops"), amended provision thereby to revise paragraph 1 of Article 7 (exclusive of the portions thereby to add provisos to item (3), and also add one item to the same paragraph), amended provisions thereby to revise Article 8 (restricted to the revision of "paragraph 3 of Article 3, and Article 4" into "Article 3, and paragraph 3 of Article 4), amended provision thereby to revise Article 9 (restricted to revision of "paragraph 3 of Article 3, and Article 4" into "Article 3, and paragraph 3 of Article 4"), amended provision thereby to revise Article 10 (restricted to "paragraph 1 of Article 5" into "paragraph 3 of Article 4 or paragraph 1 of Article 5"), amended provisions thereby to revise paragraph 2 of Article 11, Article 13, and Article 15 to 17 inclusive, amended provision thereby to add one Article following Article 18, amended provision thereby to revise Article 19, amended provision thereby to add two articles following Article 19, amended provision thereby to revise Article 20 (restricted to the revision of item (8) of Article 20 into item (9) of Article 20, and also of "item (7) of Article 20" into "item (8) of Article 20," and also the addition of one item following item (6) of Article 20), amended provision thereby to revise the Article 21 (restricted to the portions related to the group-2 substances under supervision of the portions in which to revise the specified group-1 substances into auramine, etc., or group-2 substances under supervision), amended provision thereby to revise Article 29 (restricted to the portions, related to Article 3 and paragraph 3 of Article 4, of the portions in which to revise paragraph 3 of Article 3, Article 4 or paragraph 1 of Article 5 into Article 3, paragraph 3 of Article 4, paragraph 1 of Article 5 or item (2) of paragraph 1 of Article 38-9 as set forth in item 1 of paragraph 1 of Article 29, and addition of "inclusive of local exhaust ventilation systems as set forth in the provisos in paragraph 1 of Article 3 and paragraph 1 of Article 38-12" to the portion following "local exhaust ventilation systems," and amended provisions thereby to add one chapter following Chapter V (restricted to the portions related to Article 38-12): April 1,1976.

(3)   Amended provisions thereby to revise Article 29 (restricted to the portion related to item 2 of paragraph 1 of Article 38-9, of the portions in which to revise "paragraph 3 of Article 3, Article 4 or paragraph 1 of Article 5" as set forth in item (1) of paragraph 1 of Article 29, into "Article 3, paragraph 3 of Article 4, paragraph 1 of Article 5 or item (2) of paragraph 1 of Article 38-9," and also to add "or item (3) of paragraph 1 of Article 38-9" to the portion following "paragraph 1 of Article 9" as set forth in item 2 of paragraph 1 of Article 29, and amended provision thereby to add one chapter following Chapter V (restricted to the portion related to Article 38-9): April 1, 1977

(Interim Measures)

Article 2.   In terms of the application of paragraph 1 of Article 5 of the newly revised Ordinance on Prevention of Hazards Due to Specified Chemical Substances, etc. (hereinafter called the "New Ordinance"), the portion of paragraph 1 of Article 5, which says that "indoor workshops when manufacturing specified group-2 substances, when handling the said group-2 substances in workshops therein to manufacture specified group-2 substances, where conducting fumigation therein to handle substances as set forth in (17) to (20) inclusive of item 2 in Attached Table 3 of the Enforcement Order or substances as described in item (17) to (20) inclusive in Attached Table 1 (hereinafter called methyl bromide, etc.), and when handling the substances as set forth in (30) of item 2 in Attached Table 3 or substances (hereinafter called "benzene, etc.") as described in item (30) in Attached Table 1 (inclusive of dilutants, similarly as in Article 38-12), the indoor workshops are excluded from which dispersion is made of gases, vapour or powdered dust of the specified group-2 substances" shall be defined as "indoor workshops" by December 31, 1975. 

2.  In terms of the provisos of paragraph 1 of Article 5 of the New Ordinance, the portion of paragraph 1 of Article 5, which says that "indoor workshops (when manufacturing specified group-2 substances, when handling the specified group-2 substances in workshops therein to manufacture the specified group-2 substances, when performing fumigation therein to handle the substances or set forth in (17) or (20) of item 2 in Attached Table 3 of the Enforcement Order or substances listed in (17) or (20) of item 2 of Attached Table 1 (hereinafter called "methyl bromide"), and when handling the substances listed in the (30) of item 2 in Attached Table 3 or the substances as described in item (30) in Attached Table 1 (hereinafter called "benzene, etc.") the indoor workshops are excluded from which dispersion is made of gases, vapour or powdered dust of specified group-2 substances" shall be defined as "indoor workshops (when conducting fumigation therein to handle the substances listed in (17) or (20) of item 2 in Attached Table 3 of the Enforcement Order or substances listed in item (17) or (20) in Attached Table 1, the indoor workshops are excluded from which dispersion is made of gases of these substances)" for the period of January 1, 1976 to March 31, 1976. 

3.  In terms of application of Article 3 and Article 4 of the old Ordinance on Prevention of Hazards Due to Specified Chemical Substances, "specified group-1 substances" as set forth in Article 3 shall be defined as "Auramine, etc.," and "permitted substances" as described in Article 4 shall be defined as "group-1 substances (exclusive of substances listed in (3) of item 1 of Attached Table 3 of the Enforcement Order or substances listed in (7) of item 1 in the same Table, and as related to 3 of the same item) " respectively, until March 31, 1976.

4.  When the employer performs work to put the substances, listed in (3) of item 1 in Attached Table 3 of the Enforcement Order of the Industrial Safety and Health Law, or substances (hereinafter called "chlorobiphenyl , etc." in this paragraph) listed in (7) of item 1 in the same Table and as related to 3 of the same item into containers, to take these substances out of containers or to throw the substances into reaction vessels (in the workshops therein to manufacture chlorobiphenyl, the exclusion is made of the work thereby to put chlorobiphenyl into its containers, to take the chemical out of the containers or to throw the chemical into reaction vessels), the said workshops shall be provided with local exhaust ventilation systems.

5.  In terms of the application of the provisions set forth in Article 7, Article 8 and paragraph 1 of Article 29 of the New Ordinance on the local exhaust ventilation systems as provided in compliance with the provisions in the preceding paragraph, the said local exhaust ventilation systems will be regarded as the ones provided in compliance with paragraph 1 of Article 5 of the New Ordinance.

6.  As for the facilities thereby to manufacture the substances listed in 6 of item 2 of Attached Table 3 of the Enforcement Order of the Industrial Safety and Health Law or the substances listed in item 6 in Attached Table 1 of the New Ordinance, or to handle these substances, actually existing on March 31, 1978, the said facilities are not applied to the provisions as described in Articles 4 and 5 of the New Ordinance.

7.  In terms of coke furnaces which actually exist on October 1, 1975, the furnaces will not be affected by the provisions of Article 38-9 of the New Ordinance by March 31, 1978.

8.  In terms of the application of the provisions set forth in Articles 5 and 37 of the New Ordinance, the substances, as set forth in (1), (2), (5), (6), (12), (13), (19), (20), (23), (25) to (27), (29), (30), and (34) of item 2 of Attached Table 3 of the Enforcement Order of the Industrial Safety and Health Law or the substances, as set forth in the New Ordinance in items (1), (2), (5), (6), (12), (13), (19), (20), (23), (25) to (27), (29), (30), and (34) of Attached Table 1 are not to be included among group-2 substances, as set forth in item (2) of Article 2 in the New Ordinance March 31, 1976 in spite of the provisions of the same item.

9.  In terms of the application of the provisions of Article 13 of the old Ordinance on Prevention of Hazards Due to Specified Chemical Substances, etc., and also of Articles 18 and 21 of the New Ordinance, the facilities therein to manufacture or handle the substances set forth in (1), (6), (12), (19), (20), (26), (29), (30) or (34) of item 2 in Attached Table 3 of the Enforcement Order of the Industrial Safety and Health Law or substances listed in items (l), (6), (12), (19), (20), (26), (29), (30) or (34) of Attached Table l in the New Ordinance are not to be included among those provided in Article 13 of the prior-to-revision Ordinance on Prevention of Hazards Due to Specified Chemical Substances, etc., until March 31, 1976.

Supplementary Provisions

(Ministry of Labour Ordinance No. 4 of March 25, 1976)

(Excerpt)

(Date of Enforcement)

1.  This Ministry of Labour Ordinance will be put into effect from April 1, 1976.


Supplementary Provisions

(Ministry of Labour Ordinance No. 3 of March 22, 1977)

This Ministry of Labour Ordinance will be put into effect from April 1, 1977.

Supplementary Provisions

(Ministry of Labour Ordinance No. 33 of August 16, 1978)

This Ministry of Labour Ordinance will be put into effect from September 1, 1978.

Supplementary Provisions

(Ministry of Labour Ordinance No. 18 of May 20, 1982)

(Excerpt)

(Date of Enforcement)

Article 1.  This ministerial ordinance shall be enforced from the day of its promulgation, provided that the provisions of the following subparagraphs shall be enforced from dates designated respectively in the said paragraphs.

(1)   The provision to amend Article 1 of the Ordinance for Prevention of Anoxia from among the provisions of Article 1; the provision to amend Article 2 of the said ordinance (restricted to the part expressed as "in paragraph 1 of Article 9...", which is to be deleted, and the part to add item (2) next to the said article); provisions to amend the provisions of Articles 3 through 5 of the said ordinance; provision to add another article next to the said article; provisions to amend the provisions of Articles 6, 7, 9, 10, 13, 14, 16, 17 and 23 of the said ordinance; provision to add another article next to the said article; provision to add another article next to Article 25 of the said ordinance and the provision to amend Article 27 of the said ordinance (restricted to the part expressed as "anoxia" which is to be amended as "anoxia, etc."); provision to amend item (4), paragraph 1, Article 585 of the Industrial Safety and Health Ordinance of the Industrial Safety and Health Law out of the provisions of Article 2 and the provision to amend item (4), paragraph 1, Article 640 of the said ordinance (restricted to the part expressed as "the place designated in paragraph 1 of Article 9..." in the said subparagraph, which is to be amended as "oxygen deficiency danger place designated in paragraph 1 of Article 9...") and Articles 4, 6 and 7 of the supplementary provisions: July 1, 1982.

(2)   (Omitted.)

(Interim Measures for Partial Amendment of the Ordinance for Prevention of Hazards Due to Specified Chemical Substances, etc.)

Article 7.   In applying, between July 1, 1982 and March 31, 1983, the provisions of items (1) and (2) of paragraph 1, Article 22 of the Ordinance for Prevention of Hazards Due to Specified Chemical Substances, etc., amended conforming to the provision of the preceding Article, the part expressed as "the class-2 oxygen-deficiency-danger work designated in item (8) of Article 2 and the work designated in Article 25-2 of the same ordinance..." shall be amended as "the work designated in Article 25-2."

(Interim Measures for Penal Provision)

Article 8.  The penal provision to acts committed against the provision of the old Ordinance for Prevention of Hazards Due to Specified Chemical Substances conforming to the old Ordinance for Prevention of Anoxia, the old Industrial Safety and Health Law and the provision of Article 6 of the Supplementary Provisions prior to the enforcement of this ministerial ordinance shall be applied according to precedent.

Supplementary Provisions

(Ministry of Labour Ordinance No. 3 of February 27, 1984)

(Extract)

1. This ministerial ordinance shall be enforced from March 1, 1984.


Supplementary Provision

(Ministry of Labour Ordinance No. 8 of March 18, 1986)

This ministerial ordinance shall be enforced from April 1, 1986.

Supplementary Provisions

(Ministry of Labour Ordinance No. 26 of September 1, 1988)

(Date of Enforcement)

Article 1.  This ministerial ordinance shall be enforced from October 1, 1988.

(The rest is omitted.)

(Interim Measures)

Article 2.   1. and 2. (Omitted).

3.  Concerning the measurements of the workplace where substances designated in (6)of item 1 in Attached Table 3 of the Enforcement Order (Cabinet Ordinance No. 318 of 1972) of the Industrial Safety and Health Law and the substances designated in (1) through (4), (7), (10), (11), (13), (16) through (18), (20) through (22), (25), (27), (28), (30), (31) or (33) through (35) of item 2 of the said table conducted conforming to the provision of paragraph 1 or 5, Article 65 of the Industrial Safety and Health Law before the enforcement of this ministerial order, the provisions of Articles 36-2 through 36-4 of the amended Ordinance for Prevention of Hazards Due to Specified Chemical Substances, etc., shall not be applicable.

4.   (Omitted.)

Supplementary Provisions

(Ministry of Labour Ordinance No. 30 of December 18, 1990)

This Ministry of Labour Ordinance shall be enforced from January 1, 1991.

Supplementary Provisions

(Ministry of Labour Ordinance No. 20 of  March 30, 1994)

(Excerpts)

(Date of Enforcement)

  Article 1. This Ministry of Labour Ordinance shall be enforced from July 1, 1994.

(Interim Measures concerning Notification of Plans)

  Article 2. (Omitted) Notifications based on the provisions of paragraph 1 (omitted) of Article 52 of the Ordinance on Prevention of Hazards Due to Specified Chemical Substances, etc., prior to amendment by this Ordinance (called the "old Specified Chemicals Ordinance" below) concerning construction to commence after the date of enforcement of this Ordinance (called the "Enforcement Date" below) shall be treated as valid notifications under the provisions of paragraph 1 of Article 88 of the Industrial Safety and Health Law (called the "Law" below) after the enforcement date.

  2. (Omitted) Notifications based on the provisions of paragraph 3 (omitted) of Article 52 of the old Specified Chemicals Substances concerning construction to commence after the enforcement date shall, where the provisions of paragraph 2 of the Law apply, be treated as valid notifications under the provisions of paragraph 1 of the same Article after the enforcement date.

  3. (Omitted)

  4. (Omitted)

(Interim Measures concerning Penal Provisions)

  Article 5. The application of penal provisions to acts committed before the enforcement of this Ordinance and to acts committed after the enforcement of this Ordinance that are to be treated according to precedent under the provisions of  Article 3 of the Supplementary Provisions shall be according to precedent.

Supplementary Provisions

 Ministry of Labour Ordinance No. 3 of January 16, 1995)

(Excerpts)

(Date of Enforcement)

  Article 1. This Ministry of Labour Ordinance shall be enforced from April 1, 1995. However, the provisions listed under each of the following items shall be enforced from the date specified in the relevant items.

(1)  (Omitted) The provision in Article 2 to amend Article 36-2 of the Ordinance on Prevention of Hazards Due to Specified Chemical Substances, etc.,: October 1, 1995.

(2)  (Omitted)

(Interim Measures for Evaluating the Results of Measurements, etc.)

  Article 3. The provisions of Article 36-2 through 36-4 of the amended Ordinance on Prevention of Hazards Due to Specified Chemical Substances, etc., (called the "new Specified Chemicals Ordinance" below) shall not apply to measurements in indoor workplaces of substances listed under (6) or (14) of item 2 of Attached Table 3 of the Enforcement Order of the Industrial Safety and Health Law (call the "Order" below) carried out under the provisions of paragraph 1 or paragraph 5 of Article 65 of the Law before October 1, 1995. 

  2. The provisions of Articles 36-2 through 36-4 of the new Specified Chemicals Ordinance shall not apply to measurements in indoor workplaces of substances listed under (5), (19), (23), (24), (29) or (36) of item 1 in Attached Table 3 of the Order carried out under the provisions of paragraph 1 or 5 of Article 66 of the Law before October 1, 1996.

(Interim Measures for Penal Provisions)

  Article 4. The application of penal provisions to acts committed before the enforcement of this Ordinance shall be according to precedent.

Supplementary Provisions

  (Ministry of Labour Ordinance No. 35 of September 13, 1996)

(Excerpt)

(Date of Enforcement)

  Article 1. This Ministry of Labour Ordinance shall be enforced from October 1, 1996.

Supplementary Provisions

  (Ministry of Labour Ordinance No. 13 of March 25, 1997)

(Date of Enforcement)

  This Ministry of Labour Ordinance shall be enforced from the date of promulgation.

(Interim Measures)

  Article 2. The application of penal provisions to acts committed prior to the enforcement of this Ordinance shall be according to precedent.

Supplementary Provisions

  (Ministry of Labour Ordinance No. 32 of October 1, 1997)

This Ministry of Labour Ordinance shall be enforced from the date of promulgation.

Supplementary Provisions

  (Ministry of Labour Ordinance No. 4 of January 11, 1999)

(Date of Enforcement)

  1. This Ministry of Labour Ordinance shall be enforced from the date of promulgation.

(Interim Measures)

  2. Pre-amendment forms in existence at the time of enforcement of this Ordinance may be altered and used for the interim period.



Attached Table 1 (related to Articles 2, 5, 36, 38-3, 38-7 and 38-8)

(1)   Chemicals and other substances containing acryl amide , provided that this does not apply in respect to substances which contain acryl amide of 1% or less by weight.

(2)   Chemicals and other substances containing acrylonitrile, provided that this does not apply in respect to substances which contain acrylonitrile of 1% or less by weight. 

(3)   Chemicals and other substances containing alkyl mercury compounds, provided that this does not apply in respect to substances which contain alkyl mercury compounds of 1% or less by weight

(4)   Chemicals and other substances containing asbestos (exclusive of amosite and crocidolite, the same shall apply below in this item), provided that this does not apply in respect to substances which contain asbestos of 1% or less by weight.

(5)   Chemicals and other substances containing ethyleneimine, provided that this does not apply in respect to substances which contain ethyleneimine of 1% or less by weight.

(6)   Chemical and other substances containing vinyl chloride, provided that this does not apply in respect to substances which contain vinyl chloride of 1% or less by weight.

(7)   Chemicals and other substances containing chlorine, provided that this does not apply in respect to substances which contain chlorine of 1% or less by weight.

(8)   Chemicals and other substances containing auramine, provided that this does not apply in respect to substances which contain auramine of 1% or less by weight.

(9)   Chemicals and other substances containing O-phthalodinitrile, provided that this does not apply in respect to substances which contain O-phthalodinitrile of 1% or less by weight.

(10)   Chemicals and other substance containing cadmium, provided that this does not apply in respect to substances which contain cadmium of 1% or less by weight.

(11)   Chemicals and other substances containing chromic acid or its salts, provided that this does not apply in respect to substances which contain chromic acid or its salts of 1% or less by weight.

(12)   Chemicals and other substances containing chloromethyl methyl ether, provided that this does not apply in respect to substances which contain chloromethyl methyl ether of 1% or less by weight.

(13)   Chemicals and other substances containing vanadium pentoxide, provided that this does not apply in respect to substances which contain vanadium pentoxide of 1% or less by weight.

(14)   Chemicals and other substances containing coal tar, provided that this does not apply in respect to substances which contain coal tar of 5% or less by weight.

(15)   Chemicals and other substances containing arsenic trioxide, provided that this does not apply in respect to substances which contain arsenic trioxide of 1% or less by weight.

(16)   Chemicals and other substances containing potassiumcyanide, provided that this does not apply in respect to substances which contain potassium cyanide of 5% or less by weight.

(17)   Chemicals and other substances containing hydrogencyanide, provided that this does not apply in respect to substances which contain hydrogen cyanide of 1% or less by weight.

(18)   Chemicals and other substances containing sodiumcyanide, provided that this does not apply in respect to substances which contain sodium cyanide of 5% or less by weight.

(19)   Chemicals and other substances containing 3-3'- dichloro-4-4'-diamino-diphenyl methane, provided that this does not apply in respect to substances which contain 3-3' -dichloro-4-4' - diamino-diphenyl methane of 1% or less by weight.

(20)   Chemicals and other substances containing methyl bromide, provided that this does not apply in respect to substances which contain methyl bromide of 1% or less by weight.

(21)   Chemicals and other substances containing dichromic acid or its salts, provided that this does not apply in respect to substances which contain dichromic acid or its salts of 1% or less by weight.

(22)   Chemicals and other substances containing mercury or its inorganic compounds (exclusive of mercury sulfide similarly as in the following), provided that this does not apply in respect to substances which contain mercury or its inorganic compounds of 1% or less by weight.

(23)   Chemicals and other substances containing trilene-diisocyanate, provided that this does not apply in respect to substances which contain trilene-diisocyanate of 1% or less by weight.

(24)   Chemicals and other substances containing nickel carbonyl, provided that this does not apply in respect to substances which contain nickel carbonyl of 1% or less by weight.

(25)   Chemicals and other substances containing nitroglycol, provided that this does not apply in respect to substances which contain nitroglycol of 1% or less by weight.

(26)   Chemicals and other substances containing P-dimethylaminoazobenzene, provided that this does not apply in respect to substances which contain P-dimethylaminoazobenzene of 1% or less by weight. 

(27)   Chemicals and other substances containing P-nitrochlorobenzene, provided that this does not apply in respect to substances which contain P-nitrochlorobenzene of 5% or less by weight.

(28)   Chemical and other substances containing hydrogen fluoride, provided that this does not apply in respect to substances which contain hydrogen fluoride of 5% or less by weight.

(29)   Chemicals and other substances containing ?A-propiolactone, provided that this does not apply in respect to substances which contain ?A-propiolactone of 1% or less by weight.

(30)   Chemicals and other substances containing benzene, provided that this does not apply in respect to substances which contain benzene of 1% or less by weight. 

(31)   Chemicals and other substances containing pentachlorophenol (otherwise called PCP) or its sodium salts, provided that this does not apply in respect to substances which contain pentachlorophenol or its sodium salts of 1% or less by weight.

(32)   Chemicals and other substances containingmagenta, provided that this does not apply in respect to substances which contain magenta of 1% or less by weight.

(33)   Chemicals and other substances containing manganese or its compounds (exclusive of basic manganese oxide, similarly as in the following), provided that this does not apply in respect to substances which contain manganese or its compounds of 1% or less by weight.

(34)   Chemicals and other substances containing methyl iodide, provided that this does not apply in respect to substances which contain methyl iodide of 1% or less by weight.

(35)   Chemicals and other substances containing hydrogen sulfide, provided that this does not apply in respect to substances which contain hydrogen sulfide of 1% or less by weight.

(36)   Chemicals and other substances containing dimethylsulfide provided that this does not apply in respect to substances which contain dimethylsulfide of 1% or less by weight.

Attached Table 2 (related to Article 2)

(1)   Chemicals and other substances containing ammonia, provided that this does not apply in respect to substances which contain ammonia of 1% or less by weight

(2)   Chemicals and other substances containing carbon monoxide, provided that this does not apply in respect to substances which contain carbon monoxide of 1% or less by weight.

(3)   Chemicals and other substances containing hydrogen chloride, provided that this does not apply in respect to substances which contain hydrogen chloride of 1% or less by weight.

(4)   Chemicals and other substances containing nitric acid, provided that this does not apply in respect to substances which contain nitric acid of 1% or less by weight.

(5)   Chemicals and other substances containing sulfur dioxide, provided that this does not apply in respect to substances which contain sulfur dioxide of 1% or less by weight. 

(6)   Chemicals and other substances containing phenol, provided that this does not apply in respect to substances which contain phenol of 5% or less by weight.

(7)   Chemicals and other substances containing phosgene, provided that this does not apply in respect to substances which contain phosgene of 1% or less by weight.

(8)   Chemicals and other substances containing formaldehyde, provided that this does not apply in respect to substances which contain formaldehyde of 1% or less by weight.

(9)   Chemicals and other substances containing sulfuric acid, provided that this does not apply in respect to substances which contain sulfuric acid of 1% or less by weight.

Attached Table 3 (related to Article 39)

Work

Period

Items

(1) Work to manufacture or handle the substances given below.

1) Benzidine and its salts.
2) ?A-naphthylamine and its salts.
3) Dichlorobenzidine and its salts.
4) ??-naphthylamine and its salts.
5) O-tolidine and its salts.
6) Dianisidine and its salts.
7) P-dimethylamino azobenzene.
8) Magenta.
9) Chemicals and other substances containing these substances, listed in item 1) to 8), of more than 1% by weight.

6 months

1.  Investigation of working history.

2.  Review of past history of presence of objective or subjective symptoms such as hematuria, pollakisuria, pain on urination, etc.

3.  Examination for presence of objective or subjective symptoms such as hematuria, pollakisuria, pain on urination, etc.

4.  Microscopic examination of urine sediment
(cytological examination by the Papanicolaou technique on urine sediment when regarded necessary by medical doctors).

(2) Work to manufacture or handle bis (chloromethyl) ether (inclusive of chemicals and other substances which contain bis (chloromethyl) ether of more than 1% by weight).

6 months

1.  Investigation of working history.

2   Review of past history of presence of objective or subjective symptoms such as cough, sputum, chest pain, body weight loss, etc., resulting from bis (chloromethyl) ether.

3.  Examination for presence of objective or sub-jective symptoms such as cough, sputum, chest pain, body weight loss, etc.

4.  Examination with direct roentgenography on chest on those who have been engaged in work for more than three years.

(3) Work to manufacture or handle chlorinated biphenyl.

6 months

1.  Investigation of working history.

2.  Review of past history of presence of dermatological symptoms, hepatic damage, etc., resulting from chlorinated biphenyl.

3.  Examination for presence of objective or subjective symptoms such as appetite loss, sense of weakness, etc.

4.  Examination for presence of dermatological findings such as hair follicle acne, darkening of skin, etc.

5.  Testing for urobilinogen in urine.

(4) Work to manufacture or handle beryllium, etc.

6 months

1.  Investigation of working history.

2.  Review of past history of presence of respiratory symptoms, allergic symptoms, etc., resulting from beryllium, etc.

3.  Examination for presence of objective or subjective symptoms such as dry cough, sputum, pharyngodynia, throat irritation, chest pain, chest uneasiness, shortness of breath, palpitation, difficult breathing, malaise, appetite loss, body weight loss, etc.

4.  Examination for presence of dermatological findings such as dermatitis, etc.

5.  Measurement of lung vital capacities.

 

1 year

 Direct examination of chest with roentgenography. 

(4-2)
Work to manufacture or handle benzotrichloride (inclusive of chemicals and other substances which contain benzotrichloride of more than 0.5% by weight).

6 months

1.  Investigation of working history.

2.  Review of past history of presence of objective or subjective symptoms such as cough, sputum, chest pain, nasal discharge, epistaxis, olfactory sensory loss, sinusitis, nasal polyposis.

3.  Examination for presence of objective or subjective symptoms such as cough, sputum, chest pain, nasal discharge, epistaxis, olfactory sensory, sinusitis, nasal polyposis, lymph node swelling on neck, etc.

4.  Examination for dermatological findings such as verruca, pigmentation, etc.

5.  Direct roentgenography examination of chest for those were engaged in work for more than 3 years as described in the provisions of item (9) of Article 23 of the Enforcement Order.

(5) Work to manufacture or handle acrylamide (inclusive of chemicals and substances which contain acrylamide of more than 1% by weight.)

6 months

1.  Investigation of working history.

2.  Review of past history of presence of objective or subjective symptoms such as paresthesia in extremities, gait disturbances, abnormal sweating, etc.

3.  Examination for presence of objective or subjective symptoms such as paresthesia in extremities, gait disturbances, abnormal sweating, etc.

4.  Examination for presence of dermatological findings such as dermatitis.

(6) Work to manufacture or handle acrylonitrile (inclusive of chemicals and substances which contain acrylonitrile of more than 1% by weight.)

6 months

1.  Investigation of working history.

2.  Review of past history of presence of objective or subjective symptoms such as heaviness in the head, headache, irritation in upper respiratory tract, general malaise, easy fatigue, nausea, vomiting, epistaxis, etc., resulting from acrylonitril.

3.  Examination for presence of objective or subjective symptoms such as heaviness in the head, head ache, irritation in the upper respiratory tract, general malaise, easy fatigue, chills, vomiting, nasal hemorrhage, etc.

(7) Work to manufacture or handle alkyl mercury compounds (inclusive of substances which contain alkyl mercury compounds of more than 1% of their weights.

6 months

1.  Investigation of working history.

2.  Review of past history of presence of objective or subjective symptoms such as heaviness in the head, headache, abnormal senses of lips or upper and lower extremities, althralgia, insomnia, sleepiness, depression, uneasiness, disturbance in gait, tremor in fingers, body weight loss, etc. resulting from alkyl mercury compounds.

3.  Examination for presence of objective or subjective symptoms such as abnormal senses in lips or upper and lower extremities, althralgia, insomnia, disturbance in gait, tremor in fingers, body weight loss, etc.

4.  Examination for presence of dermatological findings such as dermatitis, etc.

(8) Work to manufacture or handle asbestos, etc.

6 months

1.  Investigation of working history.

2.  Review of past history of presence of objective or subjective symptoms such as cough, sputum, shortness of breath, chest pain, etc., resulting from asbestos etc.

3.  Examination for presence of objective or subjective symptoms such as cough, sputum, shortness of breath, chest pain, etc.

4.  Direct examination of chest with roentgenography.

(9) Work to manufacture or handle ethyleneimine  (inclusive of substances which contain ethyleneimine of more than 1% by weight.)

6 months

1.  Investigation of working history.

2.  Review of past history of presence of objective or subjective symptoms such as headache, cough, sputum, chest pain, vomiting, mucous irritation symptoms, etc., resulting from ethyleneimine.

3.  Examination for presence of objective or subjective symptoms such as headache, cough, sputum, chest pain, vomiting, mucous irritation symptoms, etc.

4.  Examination for presence of dermatological findings such as dermatitis.

(10) Work to manufacture or handle vinyl chloride (inclusive of chemicals and substances which contain vinyl chloride of more than 1% by weight.)

6 months

1.  Investigation of working history.

2.  Review of past history of presence of objective or subjective symptoms such as general malaise, easy fatigue, appetite loss, uncertain upper abdominal symptoms, jaundice, tarry stools, pallidness, pain or abnormal sense in fingers, etc. resulting from vinyl chloride.

3.  Examination for presence of objective or subjective symptoms such as headache, dizziness, tinnitus, general malaise, easy fatigue, uncertain upper abdominal symptoms, jaundice, tarry stools, pain or abnormal sense in fingers, etc.

4.  Examination for presence of hepatomegaly or splenomegaly.

5.  Hepatic functional examination covering items such as serum bilirubi, serum (GOT), serum (GPT), ALP, etc.

6.  Direct examination of chest with roentgenography for those engaged in the said work for more than 10 years.

(11) Work to manufacture or handle chlorine (inclusive of substances which contain chemicals and the substances which contain chlorine of more than 1% by weight.)

6 months

1.  Investigation of working history.

2.  Review of past history of presence of objective or subjective symptoms such as respiratory symptoms, ophthalmologic symptoms, etc. resulting from chlorine.

3.  Examination for presence of objective or subjective symptoms such as cough, sputum, upper respiratory tract irritation symptoms, tearing, abnormalities of corneas, vision disturbances, dental changes, etc.

(12) Work to manufacture or handle auramine (inclusive of substances which contain suramine of more than 1% by weight.)

6 months

1.  Investigation of working history.

2.  Review of past history of presence of objective or subjective symptoms such as hematuria pollakysuria, pain on urination, etc.

3.  Examination for presence of objective or subjective symptoms such as hematuria, pollakysuria, pain on urination, etc.

4.  Microscopic examination of urine sediment (cytological examination by the Papanicolaou technique on urine sediment when found necessary by medical doctors.

5.  Testing for urobilinogen in urine.

(13) Work to manufacture or handle of O-phthalodinitrile (inclusive of substances which contain O-phthalodinitrile of more than 1% by weight.)

6 months

1.  Investigation of working history.

2.  Review of past history of presence of objective or subjective symptoms such as epilepsy-like attack.

3.  Examination for presence of objective or subjective symptoms such as headache, heaviness in the head, forgetfulness, insomnia, malaise, nausea, poor appetite, facial pallidness, tremor in fingers, etc.

4.  Testing for urobilinogen in urine.

(14) Work to manufacture or handle cadmium or its compounds (inclusive of chemicals and substances which contain cadmium or its compounds of more than 1% by weight.)

6 months

1.  Investigation of working history.

2.  Review of past history of presence of symptoms such as respiratory symptoms, gastrointestinal symptoms, etc. resulting from cadmium or its compounds.

3.  Examination for presence of objective or subjective symptoms such as cough, sputum, irritation in throat, abnormalities in nasal mucous membranes, shortness of breath, poor appetite, nausea, vomiting, repeated abdominal pain or diarrhea, body weight loss, etc.

4.  Examination for presence of cadmium accumulated in yellow circles on incisor tooth or canine tooth.

5.  Testing for presence of urinary protein.

(15) Work to manufacture or handle chromic acid, etc.

6 months

1.  Investigation of working history.

2.  Review of past history of presence of objective or subjective symptoms such as cough, sputum, chest pain, abnormalities in nasal cavity, dermatological symptoms, etc., resulting from chromic acid or bichromate.

3.  Examination for presence of objective or subjective symptoms such as cough, sputum, chest pain, etc.

4.  Examination for presence (or absence) of nasal cavity findings such as abnormalities in nasal membrane, perforation.

5.  Examination for presence of dermatological findings such as dermatitis, ulcers, etc.

6.  Direct examination of chest with roentgenography for those engaged in work, as provided in item (4) of Article 23 in the Enforcement Order, for more than 4 years.

(16) Work to manufacture or handle chloromethylmethylether (inclusive of chemicals and substances which contain chloromethylmethylether of more than 1% by weight.)

6 months

1.  Investigation of working history.

2.  Review of past history of presence of objective or subjective symptoms such as cough, sputum, chest pain, body weight loss, etc., resulting from chloromethylmethylether.

3.  Examination for presence of objective or subjective symptoms such as cough, sputum, chest pain, body weight loss, etc.

4.  Direct examination of chest with roentgenography.

(17) Work to manufacture or handle vanadium pentoxide (inclusive of chemicals and substances which contain vanadium pentoxide of more than 1% by weight.)

6 months

1.  Investigation of working history.

2.  Review of past history of presence of objective or subjective symptoms such as respiratory symptoms, etc., resulting from vanadium pentoxide.

3.  Examination for presence of objective or subjective symptoms such as cough, sputum, chest pain, dyspnea, tremor in fingers, dermatological pallidness, green tongue, cornification of the palm of fingertips, etc.

4.  Measurement of lung capacity.

5.  Measurement of blood pressure levels.

(18) Work to manufacture or handle coal tar (inclusive of chemicals or substances which contain coal tar of more than 5% by weight.)

6 months

1.  Investigation of working history.

2.  Review of past history of presence of objective or subjective symptoms such as gastrointestinal symptoms, respiratory symptoms, dermatological symptoms, etc. resulting from coal tar.

3.  Examination for presence of objective or subjective symptoms such as poor appetite, cough, sputum, ophthalmologic  pain, etc.

4.  Examination for presence of dermatological findings such as dermatitis in exposed sites, acne changes, melanosis, vernica, ulcers, gaseous spots, etc.

5.  Direct examination of chest with roentgenography for those engaged in work, as provided in item (6) of Article 23 in the Enforcement Order, for more than 5 years.

(19) Work to manufacture or handle arsenic trioxide (inclusive of chemicals or substances which contain arsenic trioxide of more then 1% by weight.)

6 months

1.  Investigation of working history.

2.  Review of past history of presence of objective or subjective symptoms such as abnormalities in nasal membrane, respiratory symptoms, stomatitis, diarrhea, constipation, body weight loss, abnormal senses, etc. resulting from arsenic trioxide.

3.  Examination for presence of objective or subjective symptoms such as cough, sputum, poor appetite, body weight loss, abnormal senses, etc.

4.  Examination for presence of nasal cavity findings such as abnormalities in nasal membrane, perforation in nasal cavity, etc.

5.  Examination for dermatological findings such as dermatitis, pigmentation, depigmentation, cornification, etc. 

6.  Testing for urinary urobilinogen levels.

7.  Direct examination of chest with roentgenography for those engaged in work, as provided in item (5) of Article 23 in the Enforcement Order, for more than 5 years.

(20) Work to manufacture or handle the substances given below.
1) Potassiumcyanide.
2) Hydrogencyanide.
3) Sodiumcyanide.
4) Chemicals and substances containing  more than 5% by weight of the chemicals and substances listed in l) or 3).
5) Chemicals and other substances containing  more than 1% by weight of the substance listed in 2).

6 months

1.  Investigation of working history.

2.  Investigation of working conditions.

3.  Review of past history of presence of objective or subjective symptoms such as heaviness in the head, headache, fatigue, malaise, hyperemia of conjunctiva, abnormaltaste, gastrointestinal symptoms, etc.

4   Examination for presence of objective or subjective symptoms such as heaviness in the head, headache, fatigue, malaise, hyperemia ofconjunctiva, abnormal taste, gastrointestinal symptoms, etc.

5   Testing of urinary urobilinogen levels.

(21) Work to manufacture or handle 3,3'-dichloro-4,4'-diaminodiphenylmethane (inclusive of substances which contain 3,3'-dichloro-4,4'- diaminodiphenylmethane of more than 1% by weights.)

6 months

1.  Investigation of working history.

2.  Review of past history of presence of objective or subjective symptoms such as abnormalities in upper abdomen, malaise, cough, sputum, chest pain, haematuria, etc., resulting from 3-3'-dichloro-4-4'diaminodiphenylmethane.

3.  Examination for presence of objective or subjective symptoms such as abnormalities in upper abdomen, malaise, cough, sputum, chest pain, haematuria, etc.

4.  Hepatic functional examination.

(22) Work to manufacture or handle methyl bromide (inclusive of chemicals or substances which contain methyl bromide of more than 1% by weight.)

6 months

1.  Investigation of working history.

2.  Review of past history of presence of objective or subjective symptoms such as heaviness in the head, headache, dizziness, tearing, rhinitis, throat pain, cough, poor appetite, nausea, vomiting, abdominal pain, diarrhea, paresthesia in upper and lower extremities, decreased sight, decreased memory, dysarthria, increased reflex in tendon, disturbances in gait, etc., resulting from methyl bromide.

3.  Examination for presence of objective or subjective symptoms such as heaviness in the head, headache, dizziness, poor appetite, paresthesia in upper and lower extremities, decreased sight, decreased memory, dysarthria, increased reflex in tendon, disturbances in gait, etc.

4   Examination for the presence of dermatological findings.

(23) Work to manufacture or handle mercury or its inorganic compounds (inclusive of chemicals and substances which contain mercury or its inorganic compounds of more than 1% by weight.)

6 months

1.  Investigation of working history.

2.  Review of past history of presence of objective or subjective symptoms such as headache, insomnia, tremor in fingers, oliguria, polyuria, inflammation of gums, stomatitis, etc., resulting from mercury or its inorganic compounds.

3.  Examination for presence of objective or subjective symptoms such as headache, insomnia, tremor in fingers, oliguria, polyuria, inflammation of gums, stomatitis, etc., resulting from mercury or its inorganic compounds.

4.  Examination for presence of urinary occult blood and protein. 

(24) Work to manufacture or handle trilenediisocyanate (inclusive of chemicals and other substances which contain trilenediisocyanate of more than 1% by weight.)

6 months

1.  Investigation of working history.

2.  Review of past history of presence of objective or subjective symptoms such as headache, ophthalmologic pain, nasal pain, throat pain, abnormal feeling in throat, cough, sputum, sense of chest compression, shortness of breath, chest pain, dyspnea, general malaise, mucous inflammation in eyes, nose, or throat, body weight loss, allergic asthma, etc., resulting from trilenediisocyanate.

3.  Examination for presence of objective or subjective symptoms such as heaviness in the head,  headache, ophthalmologic pain, nasal pain, throat pain, abnormal feeling in throat, cough, sputum, chest compression sense, shortness of breath, chest pain, dyspnea, general malaise, mucous inflammation in eyes, nose or throat, body weight loss, allergic asthma, etc.

4.  Examination for presence of dermatological findings such as dermatitis.

(25) Work to manufacture or handle nickel carbonyl (inclusive of chemicals and other substances which contain nickel carbonyl of more than 1% by weight.)

6 months

1.  Investigation of working history.

2.  Review of past history of presence of objective or subjective symptoms such as headache, dizziness, nausea, vomiting, cough, chest pain, dyspnea, itching, abnormalities in nasal mucous membrane, etc. resulting from nickel carbonyl.

3.  Examination for presence of objective or subjective symptoms such as headache, dizziness, nausea, vomiting, cough, chest pain, dyspnea, itching, abnormalities in nasal mucous membrane, etc.

 

1 year

Direct examination of chest with roentgenography.

(26) Work to manufacture or handle nitroglycol (inclusive of chemicals and other substances which contain nitroglycol of more than 1% by weight.)

6 months

1.  Investigation of working history.

2.  Review of past history of presence of objective or subjective symptoms such as headache, abnormal feeling in the chest, cardiac symptoms, paresthesia in upper and lower extremities, cooling sensation, neuralgia, malaise, etc. resulting from nitroglycol.

3.  Examination for presence of objective or subjective symptoms such as heaviness in the head, headache, stiffness in shoulders, abnormal feeling in the chest, cardiac symptoms, paresthesia in upper and lower extremities, cooling sense, neuralgia, malaise, gastrointestinal symptoms, etc.

4.  Measurement of blood pressure levels.

5.  Testing of blood in respect to its total specific gravity, and erythrocytic systems covering blood count of red blood cells, etc.

(27) Work to manufacture or handle P-nitrochlorobenzene (inclusive of chemicals or substances which contain P-nitrochlorobenzene of more than 5% by weight.)

6 months

1.  Investigation of working history.

2.  Review of past history of presence of objective or subjective symptoms such as heaviness in the head, headache, dizziness, malaise, fatigue, facial pallidness, cyanosis, anemia, palpitations, coloured urine, etc.

3.  Examination for presence of objective or subjective symptoms such as heaviness in the head, headache, dizziness, malaise, fatigue, facial pallidness, cyanosis, anemia, palpitation, coloured urine, etc.

4.  Testing for urinary urobilinogen.

(28) Work to manufacture or handle hydrogen fluoride (inclusive of chemicals or substances which contain hydrogen fluoride of more than 5% by weight.)

6 months

1.  Investigation of working history.

2.  Review of past history of presence of objective or subjective symptoms such as respiratory symptoms, ophthalmologic symptoms, etc., resulting from hydrogen fluoride.

3.  Examination for presence of objective or subjective symptoms such as mucous inflammation of the eyes, noseor mouth, change in tooth colour, etc.

4.  Examination for presence of dermatological findings such as dermatitis.

5.  Testing for urinary urobilinogen.

(29) Work to manufacture or handle β -propiolactone (inclusive of chemicals and substances which contain β-propiolactone of more than 1% by weight.)

6 months

1.  Investigation of working history.

2.  Review of past history of presence of objective or subjective symptoms such as cough, sputum, chest pain, body weight loss, etc. resulting from β-propiolactone.

3.  Examination for presence of objective or subjective symptoms such as cough, sputum, chest pain, body weight loss, etc.

4.  Examination for dermatological findings such as dermatitis in exposed sites.

5.  Direct examination of chest with roentgenography.

(30) Work to manufacture or handle benzene, etc.

6 months

1.  Investigation of working history.

2.  Review of past history of presence of objective or subjective symptoms such as heaviness in the head, headache, dizziness, palpitation, malaise, paresthesia in upper and lower extremities, poor appetite, bleeding tendency, etc. resulting from benzene.

3.  Examination for presence of objective or subjective symptoms such as heaviness in the head, headache, dizziness, palpitation, malaise, paresthesia in upper and lower extremities, poor appetite, etc.

4.  Testing of blood in respect to the total specific gravity, and erythrocytic systems covering blood count of red blood cells, etc.

5.  Testing for blood count of white blood cells.

(31) Work to manufacture or handle pentachlorophenol (otherwise called PCP) or its sodium salts (inclusive of chemicals and substances which contain pentachlorophenol and its sodium salts of more than 1% by weight.)

6 months

1.  Investigation of working history.

2.  Review of past history of presence of objective or subjective symptoms such as cough, sputum, throat pain, irritation in throat, headache, dizziness, easy fatigability, malaise, gastrointestinal symptoms such as poor appetite, preference for sweet materials, excessive sweating, fever, palpitation, ophthalmologic pain, itching, etc., resulting from pentachlorophenol or its sodium salts.

3.  Examination for presence of objective or subjective symptoms such as cough, sputum, throat pain, irritation in throat, headache, dizziness, easy fatigability, malaise, gastrointestinal symptoms such as poor appetite, preference for sweets, excessive sweating, ophthalmologic pain, itching, etc.

4.  Examination for presence of dermatological findings such as dermatitis, etc.

5.  Measurement of blood pressure levels.

6.  Testing of urinary sugar and urobilinogen.

(32) Work to manufacture or handle manganese or its compounds (inclusive of manganese or its compounds)

6 months

1.  Investigation of working history.

2.  Review of past history of presence of objective or subjective symptoms such as cough, sputum, mask-like faces, salve faces, ptyalismus, abnormal sweating, tremors in the fingers, unskillful lettering, disturbances in gait, disturbances of involuntary motion, dysarthria, etc., as in Parkinson's syndrome.

3.  Examination for presence of cough, sputum, mask-like face, salve faces, ptyalismus abnormal sweating, tremor in fingers, unskillful lettering, disturbances in gait, disturbances of involuntary motion, dysarthria as symptoms as in Parkinson's syndrome.

4.  Measurement of grasping power.

(33)  Work to manufacture or handle methyl iodide (inclusive of chemicals and other substances which contain methyl iodide of more than 1%)

6 months

1.  Investigation of working history.

2.  Review of past history of presence of objective or subjective symptoms such as heaviness in the head, dizziness, sleepiness, nausea, vomiting, malaise, dimness of sight, etc., resulting from methyl iodide.

3.  Examination for presence of objective or subjective symptoms such as heaviness in the head, dizziness, sleepiness, nausea vomiting, malaise, dimness of sight, etc.

4.  Examination for presence of dermatological findings such as dermatitis.

(34) Work to manufacture or handle hydrogen sulfide (inclusive of chemicals and other substances which contain hydrogen sulfide of more than 1% by weight.)

6 months

1.  Investigation of working history.

2.  Review of past history of presence of objective or subjective symptoms such as respiratory symptoms, ophthalmologic symptoms, etc., resulting from hydrogen sulfide.

3.  Examination for presence of objective or subjective symptoms such as headache, sleeplessness, easy fatigability, dizziness, easy excitability, nausea, cough, upper respiratory tract irritation, gastrointestinal symptoms, abnormalities in conjunctiva and cornea, changed teeth.

(35) Work to manufacture or handle dimethyl sulfide (inclusive of chemicals and other substances which contain dimethyl sulfide of more than 1% by weight.)

6 months

1.  Investigation of working history.

2.  Review of past history of presence of objective or subjective symptoms such as respiratory symptoms, ophthalmologic symptoms, dermatological symptoms, etc., resulting from dimethyl sulfide.

3.  Examination for presence of objective or subjective symptoms such as cough, sputum, hoarseness, tearing, abnormalities in conjunctivaand cornea, senses of powerlessness, gastrointestinal symptoms, etc.

4.  Examination for presence of dermatological findings such as dermatitis, etc.

5.  Testing of urinary urobilinogen or protein.

(36) Work to manufacture or handle the substances given below, for use in experimentation and research.
1) 4-aminodiphenyl and its salts.
2) 4-nitrodiphenyl and its salts.
3) Chemicals and other substances which contain substances listed in items 1) and 2) more than 1% by weight. .

6 months

1.  Investigation of working history.

2.  Review of past history of presence of objective or subjective symptoms such as hematuria, pollakysuria, pain on urination, etc.

3.  Examination for presence of objective or subjective symptoms such as hematuria, pollakysuria, pain on urination, etc.

4.  Microscopic examination of urine sediment (cytological examination by the Papanicolaou technique on urine sediment when found necessary by medical doctors.)

Attached Table 4 (related to Article 39)

Type of work

Items

(1) Work to manufacture or handle the substances given below.

1) Benzidine or its salts
2) β-naphthylamine and its salts.
3) α-naphthylamine and its salts.
4) P-dimethylaminoazobenzene.
5) Chemicals and other substances which contain substances listed in items 1) to 4) of more than 1% by weight.

1.  Investigation into working conditions.

2.  Cystoscopy or pyelography, when found necessary by medical doctors.

(2) Work to manufacture or handle the substances given below.

1) Dichlorobenzidine or its salts.
2) O-tolidine and its salts.
3) Dianisidine and its salts.
4) Magenta.
5) Chemicals and other substances which contain substances listed in items 1) to 4) of more than 1% by weight.

1.  Investigation into working conditions.

2.  Cystoscopy, when found necessary by medical doctors.

(3) Work to manufacture or handle bis (chloromethyl) ether (inclusive of chemicals and other substances which contain bis (chloromethyl) ether of more than 1% by weight.

1.  Investigation into working conditions.

2.  Examination of chest with specified roentgenography, cytological examination on sputum or bronchoscopy when found necessary by medical doctors.

(4) Work to manufacture or handle chlorinated biphenyl, etc.

1.  Investigation into working conditions.

2.  Blood testing of erythrocytic system  such as total specific gravity, blood count of red blood cells, etc.

3.  Testing for blood count of white blood cells.

4.  Hepatic functional examination.

(5) Work to manufacture or handle beryllium, etc.

1.  Investigation into working conditions.

2.  Chest physical examination.

3.  Pulmonary ventilation function examination.

4.  Pulmonary functional diffusion examination, ECC, measurement of urinary or blood beryllium levels, dermatological patching test, or measurement of hematocrit values, when found necessary by medical doctors.

(5-2)
Work to manufacture or handle benzotrichloride (inclusive of chemicals and other substances which contain benzotrichloride of more than 0.5% by weight.)

1.  Investigation into working conditions.

2.  Examination of chest with specified roentgenography, cytological examination on sputum, bronchoscopy, examination with cerebral roentgenography, etc., blood testing (inclusive of blood clinical pictures), histopathological examination of lymphatic gland or dermatological histopathological examination, when found necessary by medical doctors.

(6) Work to manufacture or handle acrylamide (inclusive of chemicals and other substances which contain acrylamide of more than 1% by weight.)

1.  Investigation into working conditions.

2.  Medical and neurological examination of peripheral nerves.

(7) Work to manufacture or handle acrylonitrile (inclusive of chemicals and other substances which contain acrylonitrile of more than 1% by weight.) 

1.  Investigation into working conditions.

2.  Measurement of plasma cholinesterase action values.

3.  Hepatic functional examination.

(8) Work to manufacture or handle alkyl mercury compounds (inclusive of chemicals and other substances which contain alkyl mercury compounds of more than 1% by weight.)

1.  Investigation into working conditions.

2.  Measurement of blood and urinary mercury levels.

3.  Examination for presence of stenosis of visual fields.

4.  Checking hearing.

5.  Medical neurological examination of abnormal senses, Rombergsign, inability to do repeatedly antagonistic motions, etc.

6.  EMG and EEG when found necessary by medical doctors in a case in which abnormal neurological findings are noted.

(9) Work to manufacture or handle asbestos, etc.

1.  Investigation into working conditions.

2.  When the results of direct examination of chest with roentgenography show abnormal shadows (exclusive of fibrous growth change), examination of chest with specific roentgenography, cytological examination on sputum, and bronchoscopy, when found necessary by medical doctors.

(10) Work to manufacture or handle ethyleneimine (inclusive of chemicals and other substances which contain ethyleneimine of more than 1% by weight.)

1.  Investigation into working conditions.

2.  Counting of bone marrow cells.

3.  Examination of chest with direct or specific roentgenography, cytological examination, bronchoscopy or renal functional examination, when found necessary by medical doctors.

(11) Work to manufacture or handle vinyl chloride (inclusive of chemical and other substances which contain vinyl chloride of more than 1% by weight.)

1.  Investigation into working conditions.

2.  Testing for platelet counts, gamma gultamiltraspepitase (?A-GTP) and Kunkel's reactions (ZTT) when hepatomegaly or splenomegaly are noted.

3.  Examination with dianogreen method (ICG), testing for lactate dehydrogenase (LDH), testing for serum lipid levels, etc., examination with specific roentgenography, examination of liver or spleen with scintigram, and medical neurological examination of central nervous systems, when found necessary by medial doctors.

(12) Work to manufacture or handle chlorine (inclusive of chemicals and other substances which contain chlorine of more than 1% by weight.)

1.  Investigation into working conditions.

2.  Chest physical examination or examination of chest with direct roentgenography.

3.  Pulmonary ventilation function examination when objective or subjective symptoms are noted in respiratory organs.

(13) Work to manufacture or handle auramine (inclusive of the chemicals and other substances which contain auramine of more than 1% by weight.)

1.  Investigation into working conditions.

2.  Cystoscopy or hepatic functional examination, when found necessary by medical doctors.

(14) Work to manufacture or handle O-phthalodinitrile (inclusive of chemicals and other substances which contain O-phthalodinitrile of more than 1% by weight.)

1.  Investigation into working conditions.

2.  Blood testing of erythrocytic system covering total specific gravity, blood count of red blood cells, etc.

3.  EEG when abnormal findings such as epilepsy-like attack are noted in cerebral nervous systems.

4.  Hepatic functional tests or measurement of urinary phthalic acid levels when gastrointestinal symptoms are noted and when found necessary by medical doctors.

(15) Work to manufacture or handle cadmium or its compounds (inclusive of chemicals and other substances which contain cadmium of more than 1% by weight.)

1.  Investigation into working conditions.

2.  Measurement of urinary cadmium levels.

3.  Chest physical examination and pulmonary ventilation function examination when objective or subjective symptoms are noted in respiratory organs.

4.  Urine sedimentation tests, measurement of urinary protein levels, and renal functional examinations when urinary protein is noted.

(16) Work to manufacture or handle chromic acid, etc.

1.  Investigation into working conditions.

2.  Examination of chest with direct or specific roentgenography, cytological examination on sputum, bronchoscopy or dermatological pathological examination, when found necessary by medical doctors.

(17) Work to manufacture or handle chloromethylmethlyether (inclusive of chemicals and substances which contain chloromethylmethylether of more than 1% by weight.)  

1.  Investigation into working conditions.

2.  Examination of chest with direct or specific roentgenography, cytological examination on sputum, or bronchoscopy, when found necessary by medical doctors.

(18) Work to manufacture or handle vanadium pentoxide (inclusive of chemicals and other substances which contain vanadium pentoxide of more than 1% by weight.)

1.  Investigation into working conditions.

2.  Examination of sight.

3.  Chest physical examination or examination of chest with direct roentgenography.

4.  Examination of pulmonary ventilation functions, measurement of serum cholesterol or triglyceride, or measurement of urinary vanadium, when found necessary by medical doctors.

(19) Work to manufacture or handle coal tar (inclusive of chemicals and other substances which contain coal tar of more than 5% by weight.)

1.  Investigation into working conditions.

2.  Examination of chest with direct or specific roentgenography, cytological examination on sputum, bronchoscopy, or dermato-pathological examination, when found necessary by medical doctors.

(20) Work to manufacture or handle arsenic trioxide (inclusive of chemicals and other substances which contain arsenic trioxide of more than 1% by weight.)

1.  Investigation into working conditions. 

2.  Examination of chest with direct or specific roentgenography, measurement of hair or urinary arsenic levels, hepatic functional test, blood testing of erythrocytic system, cytological examination on sputum, bronchoscopy, or dermato-pathological examination, when found necessary by medical doctors.

(21) Work to manufacture or handle 3,3' -dichloro-4,4' - diaminodiphenyl methane (inclusive of chemicals and other substances which contain 3,3' -dichloro-4,4' - diaminodiphenyl methane of more than 1% by weight.)

1.  Investigation into working conditions.

2.  Examination of chest with direct or specific roentgenography, cytological examination on sputum, bronchoscopy, or renal functional examination, when found necessary by medical doctors.

(22) Work to manufacture or handle methyl bromide (inclusive of chemicals and substances which contain methyl bromide of more than 1% by weight.)

1.  Investigation into working conditions.

2.  Examination of motor function, visual acuity, visual field, or EEG, when found necessary by medical doctors.

(23) Work to manufacture or handle mercury or its inorganic compounds (inclusive of chemicals and other substances which contain mercury or its inorganic compounds of more than 1% by weight.)

1.  Investigation into working conditions.

2.  Neurological examination.

3.  Measurement of urinary mercury levels and urinary sediments tests.

(24) Work to manufacture of handle trilenediisocyanate (inclusive of chemicals and other substances which contain trilene- diisocyanate of more than 1% by weight.)

1.  Investigation into working conditions.

2.  Physical examination of chest, examination of chest with direct roentgenography, or examination of occlusive changes of respiratory functions when existing subjective or objective symptoms of lungsare noted.

3.  Hepatic function tests, renal function tests, or examination of allergic reaction when found necessary by medical doctors.

(25) Work to manufacture or handle nickel carbonyl (inclusive of chemicals and other substances which contain nickel carbonyl of more than 1% by weight.)

1.  Investigation into working conditions.

2.  Examination of pulmonary ventilation functions.

3.  Physical examination of chest.

4.  Measurement of urinary or blood nickel levels when found necessary by medical doctors.

(26) Work to manufacture or handle nitroglycol (inclusive of chemicals and other substances which contain nitroglycol of more than 1% by weight.)

1.  Investigation into working conditions.

2.  Measurement of urinary or blood nitroglycol levels.

3.  Blood testing on the two items out of the measurement of hematocrit values, blood count of red blood cells and measurement of hemoglobin, when abnormalities were found as a result of the testing of blood total specific gravity.

4.  Testing for the presence of urinary urobilinogen and of protein.

5.  Examination with ECG.

6.  Examination of automatic nervous systems (exclusive of that conducted with drugs), hepatic functional examination, and circulatory functional examinationwhen found necessary by medical doctors.

(27) Work to manufacture or handle P-nitrochlorobenzene (inclusive of chemicals and other substances which contain P-nitrochlorobenzene of more than 5% by weight.)

1.  Investigation into working conditions.

2.  Blood testing of erythrocytic system covering blood total specific gravity, blood count of red blood cells, reticulocytes count, methemoglobin levels and the presence of Heinz body.

3.  Testing for urinary occult blood.

4.  Hepatic function examination.

5.  Neurological examination.

6.  Measurement of urinary aniline or P-aminophenol or measurement of metabolites in blood such as nitrosoamine and hydroxyamine, aminophenol, quinone-imine, etc., when found necessary by medical doctors.

(28) Work to manufacture or handle hydrogen fluoride (inclusive of chemicals and other substances which contain hydrogen fluoride of more than 5% by weight.)

1.  Investigation into working conditions.

2.  Chest physical examination or examination of chest with direct roentgenography.

3.  Blood testing of erythrocytic system covering total blood specific gravity, blood count of red blood cells, etc.

4.  Measurement of bleeding time, examination of long bones with roentgenography, hepatic function examination, measurement of urinary fluorine, or measurement of blood acidic phosphatase or calcium when found necessary by medical doctors.

(29) Work to manufacture or handle β-propiolactone (inclusive of chemicals and other substances which contain betapropiolactone of more than 1% by weight)

1.  Investigation into working conditions.

2.  Examination of chest with specific roentgenography, cytological examination on sputum, bronchoscopy, and dermato-pathological examination when found necessary by doctors.

(30) Work to manufacture or handle benzene, etc.

1.  Investigation into working conditions.

2.  Scanning in terms of blood covering blood pictures and others.

3.  Neurological examination.

(31) Work to manufacture or handle pentachlorophenol (otherwise called PCP) or its sodium salts (inclusive of chemicals and other substances which contain pentachlorophenol of more than 1% by weight)

1.  Investigation into working conditions.

2.  Chest physical examination and examination of chest with direct roentgenography when objective or subjective symptoms are noted in respiratory organs.

3.  Hepatic function examination.

4.  Blood count of white blood cells.

5.  Measurement of urinary pentachlorophenol, when found necessary by medical doctors.

(32) Working to manufacture or handle manganese or its compounds (inclusive of chemicals and other substances which contain manganese or its compounds of more than 1% by weight)

1.  Investigation into working conditions.

2.  Chest physical examination and examination of chest with direct roentgenography when objective or subjective symptoms are noted in respiratory organs.

3.  Neurological examination for Parkinson's-syndrome-like symptoms.

4.  Measurement of urinary or blood manganese levels, when found necessary by medical doctors.

(33) Work to manufacture or handle methyl iodide (inclusive of chemicals and other substances which contain methyl iodide of more than 1% by weight)

1.  Investigation into working conditions.

2.  Ophthalmologic examination, motor neuron function examination, or neurological examination when found necessary by medical doctors.

(34) Work to manufacture or handle hydrogen sulfide (inclusive of chemicals and other substances which contain hydrogen sulfide of more than 1% by weight)

1.  Investigation into working conditions.

2.  Chest physical examination or examination of chest with direct roentgenography.

(35) Work to manufacture or handle dimethyl sulfide (inclusive of chemicals and other substances which contain dimethyl sulfide of more than 1% by weight)

1.  Investigation into working conditions.

2.  Chest physical examination or examination of chest with direct roentgenography.

3.  Hepatic function tests, renal function tests or examination of pulmonary ventilation functions, when found necessary by medical doctors.

(36) Work to manufacture or handle the chemicals given below, for use in experimentation and research.
1) 4-aminodiphenyl and its salts.
2) 4-nitrodiphenyl and its salts.
3) Chemicals and other substances which contain substances listed in 1) and 2) of more than 1% by weight.

1.  Investigation into working conditions.

2.  Cystoscopy or pyelography, when found necessary by medical doctors.

Attached Table 5 (related to Article 39)

(1)   Chemicals and other substances containing asbestos (exclusive of amosite and crocidolite, the same shall apply below in this item), provided that this does not apply in respect to substances which contain asbestos of 1% or less by weight.

(2)   Chemicals and other substances containing ethyleneimine, provided that this does not apply in respect to substances which contain ethyleneimine of 5% or less by weight.

(3)   Chemicals and other substances containingvinyl chloride, provided that this does not apply in respect to substances which contain vinyl chloride of 1% or less by weight.

(4)   Chemicals and other substances containing auramine, provided that this does not apply in respect to substances which contain auramine of 1% or less by weight.

(5)   Chemicals and other substances containing chromic acid or its salts, provided that this does not apply in respect to substances which contain chromic acid or its salts of 1% or less by weight.

(6)   Chemicals and other substances containing chloromethylmethylether, provided that this does not apply in respect to substances which contain chloromethylmethylether of 1% or less weight.

(7)   Chemicals and other substances containing coal tar, provided that this does not apply in respect to substances which contain coal tar of 5% or less by weight.

(8)   Chemicals and other substances containing arsenic trioxide, provided that this does not apply in respect to substances which contain arsenic trioxide of 1% or less weight.

(9)   Chemicals and other substances containing 3.3'-dichloro-4.4'-diaminodiphenylmethane, provided that this does not apply in respect to substances which contain 3-3'-dichloro-4-4'-diaminodiphenylmethane of 1% or less by weight.

(10)   Chemicals and other substances containing dichromic acid or its salts, provided that this does not apply in respect to substances which contain dichromic acid or its salts of 1% or less by weight.

(11)   Chemicals and other substances containing nickel carbonyl, provided that this does not apply in respect to substances which contain nickel carbonyl of 1% or less by weight.

(12)   Chemicals and other substances containing P-dimethylaminoazobenzene, provided that this does not apply in respect to substances which contain P-dimethylaminoazobenzene of 1% or less by weight.

(13)   Chemicals and other substances containing ?A-propiolactone, provided that this does not apply in respect to substances which contain ?A-propiolactone of 1% or less by weight.

(14)   Chemicals and other substances containing benzene, provided that this does not apply in respect to substances which contain benzene of 1% or less by weight.

(15)   Chemicals and other substances containingmagenta, provided that this does not apply in respect to substances which contain magenta of 1% or less by weight.

  (Deleted)

     
     
     
     
     
     
     


Notice on Performance, as Provided by the Minister of Labour on the Basis of item (5) of Article 7 and f) of item (7) in paragraph 1 of Article 50 of the Ordinance on Prevention of Hazards Due to Specified Chemical Substances, etc.

Ministry of Labour Notice No. 75 (September 30, 1975)

Revised into Notice 26, March 25, 1976.

The performance standards given below are established by the Minister of Labour in relation to item (5) of Article 7 (inclusive of the cases in which paragraph 2 of Article 38-12 is applicable to the said item) and to f) of item (7) in paragraph 1 of Article 50 (inclusive of the cases in which paragraph 2 of Article 50-2 is applicable to this item) of the Ordinance on Prevention of Hazards Due to Specified Chemical Substances.

(1)   In terms of local exhaust ventilation systems installed in workshops therefrom to disperse gases, vapour, or dust resulting from the substances listed in (3) or (6) of item 1, or the substances as described in (8) of the same item which are related to (3) or (6) of the same item, or the substances listed in (1) to (7) inclusive, (9) to (11) inclusive, (13) to (18) inclusive, (20) to (25) inclusive, (27), (28), (30), (31) or (33) to (36) inclusive of item 2 of Attached Table 3 of the Enforcement Order of the Industrial Safety and Health Law, or the substances listed in item (1) to (7) inclusive, (9) to (11) inclusive, (13) to (18) inclusive, (20) to (25) inclusive, (27) (28), (30), (31) or (33) to (36) inclusive of Attached Table 1 of the Ordinance on Prevention of Hazards Due to Specified Chemical Substances, the concentrations of substances, as described in (3) or (6) of item 1 of Attached Table 3 of the Enforcement Order of the Industrial Safety and Health Law or the substances listed in (1) to (7), (9) to (11) inclusive, (13) to (18) inclusive, (20) to (25) inclusive, (27), (28), (30), (31) or (33) to (36) inclusive of item 2 of Attached Table 3  of the said Enforcement Order outside the hoods of local exhaust ventilation systems shall be not more than the values as established in the right column of the Table as given below corresponding to the types of the substances listed in the left column of the same Table.

Types of substances

Values

Chlorinated biphenyl (otherwise known as PCB)

0.5 mg.

Beryllium and its compounds

0.002 mg.

Acrylamide

0.3 mg.

Acrylonitrile 

45 mg. or 20 cm3

Alkyl mercury compounds (restricted to the substances in which the alkyl radicals are methyl or ethyl radicals).

0.01 mg.

Asbestos

5

Ethyleneimine

1 mg. or 0.5 cm3

Vinyl chloride

2 cm3

Chlorine

3 mg. or 1 cm3

O-Phthalodinitrile

0.1 mg.

Cadmium and its compounds

0.05 mg.

Chromic acid and its salts

0.1 mg.

Vanadium pentoxide

In terms of substances in powder: 0.5 mg.,

In terms of substances in gaseous form: 0.05 mg.

Coal tar

0.2 mg.

Arsenic trioxide

0.5 mg.

Potassium cyanate

5 mg.

Hydrogen cyanate

11 mg. or 10cm3

Sodium cyanate

5 mg.

Methyl bromide

60 mg. or 15 cm3

Dichromic acid and its salts

0.1 mg.

Mercury and its inorganic compounds (exclusive of mercurysulfide)

0.05 mg.

Trilenediisocyanate

0.12 mg. or 0.02 cm3

Nickel carbonyl

Nitroglycol

0.007 mg. or 0.001 cm3

1.2mg. or 0.2cm3

P-Nitrochlorobenzene

1 mg.

   

Hydrogen fluoride

2 mg. or 3 cm3

Benzene

30 mg. or 10 cm3

Pentachlorophenol (otherwise known as PCP) and its sodium salts

0.5 mg.

Manganese and its compounds (exclusive of basic manganese oxides)

5 mg.

Methyl iodide

28 mg. or 5 cm3

Hydrogen sulfide

15 mg. or 10 cm3



INDEX
I / II / III / IV / V / V-II
VI / VII / VIII / IX / X / Supplementary Provisions



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